From 1948 Sir Barry returned to oversee the work at the Birmingham Repertory Theatre. The administration of the theatre was carried out by Nancy Burman. Celebrated productions during this period include the three parts of Henry VI (1953) directed by Douglas Seale and the revival of Shaw's Caesar and Cleopatra (1956) that was performed at the International Theatre Festival in Paris.
Throughout the late 1950s plans were developed for a new theatre building in Birmingham and in 1960 the City Council and the Arts Council agreed funding would be provided. However, Sir Barry did not live to see the new Rep on Broad Street (1971). After a long period of severe illness, Sir Barry Jackson died on 3 April 1961, at the Queen Elizabeth Hospital in Birmingham.